Sildenafil generic is a well-known anti-erectile dysfunction medicine all over the world. Sildenafil generic is a medicine that is mainly used for the treatment of men’s erectile dysfunction and it is also used for the treatment of pulmonary arterial hypertension. Sildenafil generic is not intended for women as its effect is not thoroughly clear.
The action of sildenafil generic, once taken in by mouth, is that it stops or inhibits the activity of the enzyme called cGMP-specific PDE5 (phosphodiesterase type 5). This particular enzyme is the one responsible for degrading cGMP, which actually regulates the penile blood flow. Three Pfizer scientists have originally discovered sildenafil generic and ever since it has been released to the market in the year 1998, sildenafil generic has become a household name when it comes to treating erectile dysfunction in men.
There are actually many uses of sildenafil generic, both in the medical and non-medical fields. The proven medical uses of sildenafil generic are mainly two: for sexual dysfunction or erectile dysfunction and for pulmonary arterial hypertension. The primary use for the existence of sildenafil generic is obviously for treating men’s problems associated with erectile dysfunction, which is the failure to obtain and maintain penile erection that is good enough for sexual intercourse. Nowadays, sildenafil generic is considered as a standard treatment for erectile dysfunction cases, including patients who are also suffering from diabetes mellitus. Sildenafil generic is fortunately also indicated in patients who have the rare disorder pulmonary arterial hypertension. Sildenafil generic effectively makes the arterial walls to relax, which leads to a minimized or lowered resistance and pressure being put on the pulmonary arteries. This results to the reduced workload of the heart’s right ventricle, thereby improving signs and symptoms of right-sided heart failure in men. Due to the fact that PDE5 is mainly present within the penis and the lungs’ arterial wall smooth muscle, the action of sildenafil generic is selective in these two areas, meaning they do not induce any vasodilation in other parts of the body.
The uses of sildenafil generic in the non-medical setting include the following: for recreational use, sports and jet lag research. For recreational use, sildenafil generic was widely known in pop culture and the main reasons why it has become so popular is because people strongly believed that sildenafil generic an increase one’s sexual libido, improve performance in bed, or that it can permanently make the penis bigger in size. In sports, pro athletes have turned to using sildenafil generic, believing that their blood vessels will open more to enhance their muscles. This will result to their performances being enhanced. In jet lag research, sildenafil generic was discovered to be helpful in jet lag recovery when tested in hamsters. (more…)
17 May 2015